描述
开 本: 16开纸 张: 胶版纸包 装: 平装是否套装: 否国际标准书号ISBN: 9787312022203丛书名: 当代科学技术基础理论与前沿问题研究丛书
编辑推荐
本书为英文版，系统介绍了人工肾的起源、结构系统、工作原理及发展前景，详细论述了多种人工肾数理模型和计算机模拟优化方法，并运用大量实例阐述了人工肾实验研究方法。
全书包括了Introduction、Numerical Analyses of Mass Transfer in Artificial Kidney、In Vitro Experimental Study of Hemodialysis等六个部分的内容。
全书包括了Introduction、Numerical Analyses of Mass Transfer in Artificial Kidney、In Vitro Experimental Study of Hemodialysis等六个部分的内容。
内容简介
本书系统介绍了人工肾的起源、结构系统、工作原理及发展前景，详细论述了多种人工肾数理模型和计算机模拟优化方法，并运用大量实例阐述了人工肾实验研究方法。本书适合生物医学工程、临床医学、血液透析、膜科学、传热传质、化工领域的学生、教师以及研究人员阅读，可作为相应课程的教学参考书及新型人工肾研发的实用手册。
目 录
Preface to the USTC Alumni’s Series
List of Symbols
Section Ⅰ Introduction
Chapter 1 Human Kidneys
1.1 Function and Structure of Human Kidney
1.2 Kidney Failure
1.3 End-Stage Renal Disease
1.4 Classification of Uremic Solutes
Chapter 2 Artificial Kidneys
2.1 Function and Structure of Artificial Kidney
2.2 Major Milestones of Artificial Kidney Development
2.3 Classification of Artificial Kidneys
2.4 Dialysis Membranes
Chapter 3 Transport in Artificial Kidneys
3.1 Diffusive Transport
3.2 Convective Transport
3.3 Coupled Diffusive-Convective Transport
References
Section Ⅱ Numerical Analyses of Mass Transfer in Artificial Kidney
Chapter 4 Equivalent Annulus Model
4.1 Introduction
4.2 Modeling
4.3 Numerical Algorithm
4.4 Results and Discussion
4.5 Conclusions
Chapter 5 Porous Media Model
5.1 Introduction
5.2 Modeling and Algorithm
5.3 Results and Discussion
5.4 Conclusions
Chapter 6 Double Porous Media Model
6.1 Introduction
6.2 Theory
6.3 Simulation Conditions
6.4 Validation of Model
6.5 Conclusions
Chapter 7 Determinations of Membrane Properties and Parameters
7.1 Introduction
7.2 Preparation of Mini-Module Dialyzer
7.3 Selection of Solutes
7.4 Measurement of Hydraulic Permeability
7.5 Measurement of Diffusive Permeability
7.6 Measurement of Reflection Coefficient
7.7 Sample Assays
7.8 Calculation of Pore Size
7.9 Measurement of Darcy Permeability
Chapter 8 Kinetic Modeling in Hemodialysis
8.1 Introduction
8.2 Simulation of Continuous Renal Replacement Therapy(CRRT)
8.3 Intermittent Hemodialysis and Sustained Low-EfficiencyDialysis
8.4 Results and Discussion
8.5 Conclusions
References
Section Ⅲ In Vitro Experimental Study of Hemodialysis
Chapter 9 Introduction to General in Vitro Methodologies
9.1 Hemodialyzers and Hemofilters
9.2 Experimental Solutes
9.3 System Setup
9.4 Data Analysis
Chapter 10 Local Clearance of Hemodialyzer
10.1 Introduction
10.2 Materials and Methods
10.3 Experiment Setup
10.4 Data Collection and Analysis
10.5 Results and Discussion
10.6 Conclusions
Chapter 11 Effects of Dialyzer Reprocessing
11.1 Introduction
11.2 Materials and Methods
11.3 Results and Discussion
11.4 Conclusions
Chapter 12 Cytokine-Induced Substance Back Transport in a High Flux Dialyzer
12.1 Introduction
12.2 Materials and Methods
12.3 Results
12.4 Discussion
12.5 Conclusions
Chapter 13 A Study of Dilution Mode and Ultrafiltration Rate in a High Volume Continuous Hemofiltration
13.1 Introduction
13.2 Materials and Methods
13.3 Assays
13.4 Results
13.5 Conclusions
Chapter 14 Determinants of Solute Clearance in Hemodiafiltration
14.1 Introduction
14.2 Purpose
14.3 Materials and Methods
14.4 Assays
14.5 Results and Discussion
14.6 Conclusions
References
Section Ⅳ Novel MRI Approach for Flow Field Measurement
Chapter 15 Basic Principles of MRI
15.1 Magnetic Properties of Atomic Nuclei
15.2 Relaxation Processes
15.3 Standard Imaging Pulse Sequences
15.4 Magnetic Resonance Flow-Imaging Techniques
Chapter 16 Experimental Design and Image Analysis
16.1 Flow Phantom
16.2 2-D Phase-Contrast Study
16.3 2-D Fourier-Transform Study
16.4 Results of 2-D Phase-Contrast Study
16.5 Results of 2-D Fourier-Transform Study
References
Section Ⅴ Advances in New Membrane Development
Chapter 17 Ceramic Membrane for Hemodialysis
17.1 Introduction
17.2 Principle of Aluminum Anodization
17.3 Materials and Methods
17.4 Results and Discussion
17.5 Conclusions
Chapter 18 Bio-functional Artificial Kidney
18.1 Current Status of Therapy for Renal Failure
18.2 Bioengineered Kidney
References
List of Symbols
Section Ⅰ Introduction
Chapter 1 Human Kidneys
1.1 Function and Structure of Human Kidney
1.2 Kidney Failure
1.3 End-Stage Renal Disease
1.4 Classification of Uremic Solutes
Chapter 2 Artificial Kidneys
2.1 Function and Structure of Artificial Kidney
2.2 Major Milestones of Artificial Kidney Development
2.3 Classification of Artificial Kidneys
2.4 Dialysis Membranes
Chapter 3 Transport in Artificial Kidneys
3.1 Diffusive Transport
3.2 Convective Transport
3.3 Coupled Diffusive-Convective Transport
References
Section Ⅱ Numerical Analyses of Mass Transfer in Artificial Kidney
Chapter 4 Equivalent Annulus Model
4.1 Introduction
4.2 Modeling
4.3 Numerical Algorithm
4.4 Results and Discussion
4.5 Conclusions
Chapter 5 Porous Media Model
5.1 Introduction
5.2 Modeling and Algorithm
5.3 Results and Discussion
5.4 Conclusions
Chapter 6 Double Porous Media Model
6.1 Introduction
6.2 Theory
6.3 Simulation Conditions
6.4 Validation of Model
6.5 Conclusions
Chapter 7 Determinations of Membrane Properties and Parameters
7.1 Introduction
7.2 Preparation of Mini-Module Dialyzer
7.3 Selection of Solutes
7.4 Measurement of Hydraulic Permeability
7.5 Measurement of Diffusive Permeability
7.6 Measurement of Reflection Coefficient
7.7 Sample Assays
7.8 Calculation of Pore Size
7.9 Measurement of Darcy Permeability
Chapter 8 Kinetic Modeling in Hemodialysis
8.1 Introduction
8.2 Simulation of Continuous Renal Replacement Therapy(CRRT)
8.3 Intermittent Hemodialysis and Sustained Low-EfficiencyDialysis
8.4 Results and Discussion
8.5 Conclusions
References
Section Ⅲ In Vitro Experimental Study of Hemodialysis
Chapter 9 Introduction to General in Vitro Methodologies
9.1 Hemodialyzers and Hemofilters
9.2 Experimental Solutes
9.3 System Setup
9.4 Data Analysis
Chapter 10 Local Clearance of Hemodialyzer
10.1 Introduction
10.2 Materials and Methods
10.3 Experiment Setup
10.4 Data Collection and Analysis
10.5 Results and Discussion
10.6 Conclusions
Chapter 11 Effects of Dialyzer Reprocessing
11.1 Introduction
11.2 Materials and Methods
11.3 Results and Discussion
11.4 Conclusions
Chapter 12 Cytokine-Induced Substance Back Transport in a High Flux Dialyzer
12.1 Introduction
12.2 Materials and Methods
12.3 Results
12.4 Discussion
12.5 Conclusions
Chapter 13 A Study of Dilution Mode and Ultrafiltration Rate in a High Volume Continuous Hemofiltration
13.1 Introduction
13.2 Materials and Methods
13.3 Assays
13.4 Results
13.5 Conclusions
Chapter 14 Determinants of Solute Clearance in Hemodiafiltration
14.1 Introduction
14.2 Purpose
14.3 Materials and Methods
14.4 Assays
14.5 Results and Discussion
14.6 Conclusions
References
Section Ⅳ Novel MRI Approach for Flow Field Measurement
Chapter 15 Basic Principles of MRI
15.1 Magnetic Properties of Atomic Nuclei
15.2 Relaxation Processes
15.3 Standard Imaging Pulse Sequences
15.4 Magnetic Resonance Flow-Imaging Techniques
Chapter 16 Experimental Design and Image Analysis
16.1 Flow Phantom
16.2 2-D Phase-Contrast Study
16.3 2-D Fourier-Transform Study
16.4 Results of 2-D Phase-Contrast Study
16.5 Results of 2-D Fourier-Transform Study
References
Section Ⅴ Advances in New Membrane Development
Chapter 17 Ceramic Membrane for Hemodialysis
17.1 Introduction
17.2 Principle of Aluminum Anodization
17.3 Materials and Methods
17.4 Results and Discussion
17.5 Conclusions
Chapter 18 Bio-functional Artificial Kidney
18.1 Current Status of Therapy for Renal Failure
18.2 Bioengineered Kidney
References
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